receiver operating characteristic – Communicable Diseases Research

Association of iron-related biomarkers with severity and mortality in COVID-19 patients

Article

Published on 2022-12-012022-11-15
Journal: Journal of trace elements in medicine and biology
[Category] COVID19(2023년), SARS, 바이오마커, 치료기술,

Evaluation of commercially available fully automated and ELISA-based assays for detecting anti-SARS-CoV-2 neutralizing antibodies

Article

Published on 2022-11-082022-11-15
Journal: Scientific Reports
[Category] SARS, 치료기술,

[키워드] acute respiratory syndrome administration affecting Analysis analysis anti-RBD IgG antibody anti-SARS-CoV-2 AUC automated binding antibody booster clinical settings Cohort collected Control coronavirus correlation COVID-19 cutoff value demonstrated Effectiveness Genscript gold standard Immunity immunoassay in both groups infected patient Mindray NAb neutralization Neutralization assay neutralization test neutralizing antibody population level protective immunity provide pseudovirus R 2 Rapid receiver operating characteristic Research ROC ROC Curve Sample SARS-CoV-2 SARS-CoV-2 infected patient second dose sensitivity shown significantly specificity subjects sVNT sVNT assay symptoms onset tested threshold vaccinated individual Vaccine virus neutralization test was performed
[DOI] 10.1038/s41598-022-21317-x PMC 바로가기

Rapid Cytokine Release Assays for Analysis of Severe Acute Respiratory Syndrome Coronavirus 2-Specific T Cells in Whole Blood

전혈에서 중증 급성 호흡기 증후군 코로나바이러스 2-특이적 T 세포 분석을 위한 신속한 사이토카인 방출 분석

Article

Published on 2022-08-242022-09-11
Journal: The Journal of Infectious Diseases
[Category] SARS, 진단, 치료법,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed anti-receptor-binding domain antibody Blood samples characteristic clinical complicate Complication controls coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine cytokine Cytokine release assay diagnosed Diagnosis Diagnostic accuracy Donor EudraCT evaluated exhibited high accuracy IgG IgG levels Immunoglobulin Immunoglobulin G induction Infection interferon interferon γ memory memory response nucleocapsid Patient peptide peptides plasma Previous studies protocol Rapid receiver receiver operating characteristic Region Release remained respiratory SARS-CoV-2 seropositive serum severe acute respiratory syndrome Coronavirus Spike. stimulated study participant supernatant T cells T-cell T-cell immunity Trial vaccine doses waned Whole blood
[DOI] 10.1093/infdis/jiac005 PMC 바로가기 [Article Type] Article

Validation of a noninvasive aMMP-8 point-of-care diagnostic methodology in COVID-19 patients with periodontal disease

Article

Published on 2022-08-012022-11-16
Journal: Clinical and Experimental Dental Research
[Category] 치료기술,

Assessment of thromboembolism risk in COVID-19 patients with cardiovascular disease risk factors: Analysis of a Japanese Nationwide Registry

Research article

Published on 2022-08-012022-10-05
Journal: Thrombosis research
[Category] COVID19(2023년), SARS, 바이오마커,

[키워드] abnormality Accuracy Acute kidney injury acute respiratory distress syndrome adjusted Admission AKIAcute Kidney Injury Analysis ARDSacute respiratory distress syndrome area under the curve assessment AUCarea under the curve BNPbrain natriuretic peptide brain natriuretic peptide C-reactive protein cardiovascular disease cardiovascular disease risk factor chest X-ray Coagulation coefficient cohort study confidence interval coronavirus disease-2019 COVID-19 patient COVID-19coronavirus disease-2019 CRPC-reactive protein CVDRFcardiovascular disease risk factor D-dimer D-dimer level Deep vein thrombosis develop DVTdeep vein thrombosis embolic event Factor Hospitalization hospitalized patient identify In-hospital in-hospital mortality Invasive mechanical ventilation Japanese lactate dehydrogenase LASSOleast absolute shrinkage and selection operator LDHlactate dehydrogenase least absolute shrinkage and selection operator limitation Male sex N-terminal prohormone of brain natriuretic peptide NT-pro-BNPN-terminal prohormone of brain natriuretic peptide Occurrence operator parameter Patient patients with COVID-19 potential risk Predictive Predictive model PTEpulmonary thromboembolism Pulmonary thromboembolism receiver operating characteristic reducing Registered registry reported Result risk risk factor ROCreceiver operating characteristic shown significantly Support the primary endpoint thromboembolic Thromboembolic events Thromboembolism Venous Thromboembolism VTEVenous Thromboembolism was performed WBCWhite blood cell White blood cell with COVID-19
[DOI] 10.1016/j.thromres.2022.06.007 [Article Type] Research article

Using artificial intelligence to improve the diagnostic efficiency of pulmonologists in differentiating COVID-19 pneumonia from community-acquired pneumonia

인공 지능을 사용하여 지역사회 획득 폐렴과 COVID-19 폐렴을 구별하는 호흡기 전문의의 진단 효율성 향상

Article

Published on 2022-08-012022-09-11
Journal: Journal of medical virology
[Category] COVID19(2023년), SARS, 치료기술,

Clinical and laboratory profiles of the SARS-CoV-2 Delta variant compared with pre-Delta variants

델타 이전 변이와 비교한 SARS-CoV-2 Delta 변이의 임상 및 실험실 프로필

Article

Published on 2022-07-012022-09-11
Journal: International Journal of Infectious Diseases
[Category] COVID19(2023년), SARS, 변종,

[키워드] activated C-reactive protein can be used Care changes in characteristic Characteristics characterized clinical Clinical data Cohort Comorbidities comparison Comparisons COVID-19 defined Delta delta variant Department Descriptive statistics ferritin fibrinogen genomic Genomics Gradient Gradient boosting model heterogeneous hospitalizations hospitalized patients Human identify implication Inflammatory intensive care intensive care unit International international normalized ratio Laboratory laboratory characteristics Lactate lactate dehydrogenase machine machine learning machine learning approach machine learning approaches Negative predictive value normalized Patient peaked phenotypical Positive predictive value Predictive value profile prothrombin Prothrombin time public health measures receiver receiver operating characteristic Research Retrospective study SARS-CoV-2 variant SARS-CoV-2 variants sensitivity service single-center specificity supported the SARS-CoV-2 the United State THROMBOPLASTIN Transmissibility Treatment protocol United States variant variants variants of concern. virulence Wave Waves were used
[DOI] 10.1016/j.ijid.2022.04.050 PMC 바로가기 [Article Type] Article

The polymorphism L412F in TLR3 inhibits autophagy and is a marker of severe COVID-19 in males

TLR3의 다형성 L412F는 자가포식을 억제하고 남성에서 심각한 COVID-19의 표지자입니다

Article

Published on 2022-07-012022-09-11
Journal: Autophagy
[Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analysis association autoantigen autoimmune disorder Autoimmune disorders autophagosome autophagy autophagy pathways bafilomycin clinical trial clinical trials co-morbidity Cohort coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 patients demonstrated Diseases Frequency HEK293 cell HEK293 cells HLA HLA haplotype Hydroxychloroquine Impaired increases in Infectious diseases inhibit L412F male males marker mechanism morbidity Necrosis Plasmid poly(I:C) polymorphism provide Rapamycin rationale receiver operating characteristic receptor reduced respiratory risk severe acute respiratory syndrome Coronavirus severe COVID-19 severity shown statistically significant stimulated sub-cohort survival TLR3 TLR3. TNFα transfected with treated Tumor tumor necrosis tumor necrosis factor
[DOI] 10.1080/15548627.2021.1995152 PMC 바로가기 [Article Type] Article

Sensitive and specific clinically diagnosis of SARS-CoV-2 employing a novel biosensor based on boron nitride quantum dots/flower-like gold nanostructures signal amplification

질화붕소 양자점/꽃모양 금 나노구조 신호 증폭 기반의 새로운 바이오센서를 이용한 SARS-CoV-2의 민감하고 구체적인 임상 진단

Article

Published on 2022-07-012022-09-11
Journal: Biosensors & bioelectronics
[Category] COVID19(2023년), SARS, 치료기술, 치료제,

[키워드] amplification biosensor Boron boron nitride carbon characteristic clinical sample clinical samples clinical trials clinically comparable COVID-19 COVID-19 outbreak COVID-19 pandemic cross-reactivity cutoff value Detection limit Diagnosis diagnosis of SARS-CoV-2 DNA Effect electrochemical biosensor evaluate form gold group growth Health Health crisis IAV Influenza influenza A Mutation nucleic acid nucleic acid amplification Patient platform point-of-care positive quantitation Quantitative receiver operating characteristic receiver operating characteristic curve remained RNA RNA fragment RT-PCR SARS-CoV-2 SARS-CoV-2 RNA Screen sensitive sensitivity significant difference specificity ssDNA statistical analysis t-test Virus diagnosis. was tested
[DOI] 10.1016/j.bios.2022.114209 PMC 바로가기 [Article Type] Article

Development of a Mortality Prediction Model in Hospitalised SARS-CoV-2 Positive Patients Based on Routine Kidney Biomarkers

일상적인 신장 바이오마커를 기반으로 입원한 SARS-CoV-2 양성 환자의 사망률 예측 모델 개발

Article

Published on 2022-06-302022-09-11
Journal: International Journal of Molecular Sciences
[Category] COVID19(2023년), MERS, SARS, 바이오마커,

[키워드] Acute kidney injury acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age AKI an area analysed AUROC Biomarker Blood blood test blood tests characteristic Cohort coronavirus COVID-19 creatinine develop development Ethnicity focus foundation hospital hospitalised Humber in-hospital mortality increased mortality Inpatients kidney Kidney function kidney function test Kidney function tests Kidney injury Logistic regression logistic regression model main outcome measure Model Mortality National Health Service NHS outcome Patient patients without AKI PCR test positive positive RT-PCR prediction prediction model. predictor prevalent random Random forest receiver operating characteristic regions respiratory resulting retrospective cohort study routine RT-PCR test SARS-CoV-2 SARS-CoV-2 infected patients SARS-CoV-2 positive patient SARS-CoV-2 positive patients severe acute respiratory syndrome Coronavirus Sex sodium test dataset Trust United Kingdom urea
[DOI] 10.3390/ijms23137260 PMC 바로가기 [Article Type] Article